On this episode of the RLP podcast, I discuss fluconazole pharmacology.

Fluconazole prevents fungi from producing essential components for their cell membrane and thus inhibits their growth.

Drug interactions are common with fluconazole. Fluconazole inhibits CYP3A4, 2C9, and 2C19 to varying degrees.

I discuss an interaction between fluconazole and phenytoin in this podcast episode.

Hepatitis has rarely been reported with the use of azole antifungals like fluconazole.