In this episode of the RLP podcast, I discuss scopolamine pharmacology. Scopolamine patches can be used in the management of motion sickness and surgery/anesthesia induced nausea and vomiting. Transdermal scopolamine has a slow onset of action so we need to be deliberate about the timing of placement (usually 4-6 hours prior to anticipated time of symptoms). Transdermal scopolamine is highly anticholinergic and can cause dry eyes, dry mouth, urinary retention, and confusion.