On this podcast episode, I discuss acamprosate pharmacology, adverse effects, drug interactions, and much more!

Acamprosate’s most common adverse effect is diarrhea. It is a primary reason why patients will ask to stop taking this medication.

It is critical to assess renal function prior to using acamprosate. Dose adjustments are recommended when patients have a CrCl of less than 50 ml/min.

Unlike naltrexone, acamprosate avoids liver metabolism making it an alternative option in alcohol use disorder for patients who have liver impairment.

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