Humans are pushed further in personal virtual interactions, navigating online conversations with minds programmed to take cues from facial expressions, tone of voice, and other missing nuances of in-person communication. This struggle to perceive meaning and truth includes our reading of news, which can include “fake news.” Dr. Eric C. Leuthardt and Dr. Albert H. Kim, Washington University neurosurgeons at Barnes-Jewish Hospital, discuss the effects of engaging with people and information in a virtual space.