Guest:

Dr. Alice Soragni is an Associate Professor at the University of California, Los Angeles. She talks about her work on patient-derived organoids and how they can be adapted for drug screening. She also discusses how she transitioned from structural biology to research on protein aggregation and rare diseases, and the current social media landscape for scientists. (45:20)

Featured Products and Resources:

• Download a free wallchart on the applications of organoid cultures.
• Take your human pluripotent stem cell cultures further with mTeSR™ Plus.

The Stem Cell Science Round Up

Optogenetic Control of Morphogen Production – Researchers established a model that recapitulates Sonic hedgehog-mediated patterning of the vertebrate neural tube. (4:17)

Oligodendrocyte Maturation – Reducing SOX6 levels unlocks oligodendrocyte maturation and myelination. (15:45)

CAR T Therapy for Kidney Disease – Targeting extracellular matrix-producing cells with CAR T therapy is a therapeutic strategy for chronic kidney disease. (24:44)

Lung Xenotransplantation – A lung from a gene-edited pig was transplanted into a brain-dead human recipient. (35:00)

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