Guest:

Dr. Sarah Teichmann is a Member of the Department of Medicine and Professor of Stem Cell Medicine at the Cambridge Stem Cell Institute.  She talks about the plasticity of different cell types and developing whole-organ cell atlases for organs such as the thymus. She also discusses the Human Cell Atlas project and overcoming skepticism in its early days. Finally, she talks about integrating computational with wet lab biology, and running an interdisciplinary research group. (43:30)

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The Stem Cell Science Round Up

Parkinson’s Disease Cell Therapy Trials – Two trials confirm the safety of stem cell-derived dopaminergic neurons for Parkinson’s disease. (1:30)

Multi-Zonal Liver Organoids – Researchers developed a self-assembling zone-specific liver organoid to evaluate hepatic zonal polarity. (13:23)

Protein Delivery to the Brain – iPSC-microglia can be harnessed to provide a promising new cell therapy platform. (22:00)

Blood Vessel Organoids – Transcription factor-based programming of blood vessel organoids promotes brain vasculature specificity. (33:33)

Image courtesy of Dr. Sarah Teichmann

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