April 06, 2022

Today we talk about BRUE – brief, resolved, unexplained, events – and try to breakdown what it is and what we do for low-risk versus high-risk cases. 


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This episode was written by Dr. Tammy Yau and Dr. Lidia Park with content support from Dr. Eunice Kim, Dr. Lena van der List, and Dr. Su-Ting Li. Drs. Tammy and Lidia take full responsibility for any errors or misinformation. 

Key points: 

-Brief, resolved, unexplained events in patients <1 year of age with color change, tone change, abnormal breathing, or altered level of consciousness. 

-BRUE can be classified as low versus high risk based on age of patient, frequency of events, and other concerning exam or history findings 

-Only brief observation is needed in low risk BRUE. However high risk BRUE requires more extensive workup. 


Supplemental information: 

AAP 2016 guidelines for low-risk infants: 

AAP 2019 guidelines for high-risk infants: