Guest:

Dr. Vijay Kuchroo is the Samuel L. Wasserstrom Professor of Neurology at Harvard Medical School. His major research interests include the role of co-stimulation in autoimmune diseases, as well as cell surface molecules and regulatory factors that regulate the induction of T cell tolerance and dysfunction. He talks about the conditions necessary to differentiate Th17 cells and their role in autoimmunity. He also discusses his group’s discovery of Tim-3, an inhibitor receptor on T cells which is now being exploited for cancer immunotherapy.

Featured Products and Resources:

• Resources for Your T Cell Therapy Research
• Read interviews where immunologists tell their stories, discuss their research, and voice their thoughts and opinions on current topics in immunology.

The Immunology Science Round Up

Disrupting Calcium Homeostasis – Researchers showed that inherited variants in ITPR3 alter physiologically relevant Ca2+ signaling responses, driving defects in immune responses.

Light Chain Coherence in Antibodies – Among naturally occurring antibodies that have adapted to particular antigens, those with similar heavy chains usually have similar light chains.

Anti-CTLA-4 Antibodies Reprogram the Tumor Microenvironment – Scientists used single-cell RNA sequencing to dissect the immune response to anti-CTLA-4 blockade.

An Intranasal Booster for Sarbecoviruses – Researchers used a SARS-CoV-2 intranasal spike booster to elicit mucosal immune memory within the respiratory tract.

Image courtesy of Dr. Vijay Kuchroo

#footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } Subscribe to our newsletter!

Never miss updates about new episodes.

Subscribe