Guest:

Dr. Susan Kaech is a Professor and Director of the NOMIS Center for Immunobiology and Microbial Pathogenesis at the Salk Institute. Her lab aims to understand how memory T cells are produced during infection and vaccination, how they function, and why they can fail to induce long-term immunity, particularly during chronic disease or cancer. In this episode, she talks about her research on T cell exhaustion and neuroimmunology, as well as her path from genetics to immunology.

Featured Products and Resources:

• Keep current with the latest in human immunology news.
• Achieve robust T cell expansion with ImmunoCult-XF.

The Immunology Round Up

Glycan Breakdown and Bacterial Function – Researchers used a large-scale screen to identify enzyme systems that represent an underappreciated mode of glycan degradation.

Cancer Risk after CAR T Therapy – Only a small percentage of patients who receive CAR T therapies develop secondary cancers, and most are not directly linked to CAR T treatment.

CD8+ T Cells in Hepatitis B – Hepatocellular priming induces key co-signaling receptors in dysfunctional CD8+ T cells.

T Cell Aging – T cell epigenetic clocks measure replicative history and can continue to accumulate well-beyond organismal lifespan.

Image courtesy of Dr. Susan Kaech

#footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } #footable_4813 { font-family: inherit; font-size: 14px; } #footable_parent_4813 thead { display: none; } #footable_parent_4813 a.nt_edit_link { display: none; } #footable_parent_4813 td { border-color: #fff; } #footable_parent_4813 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; }#footable_4813 td.ninja_column_0 { text-align: center; }#footable_4813 th.ninja_column_0 { text-align: center; } #footable_4814 { font-family: inherit; font-size: 14px; } #footable_parent_4814 thead { display: none; } #footable_parent_4814 a.nt_edit_link { display: none; } #footable_parent_4814 td { border-color: #fff; } #footable_parent_4814 img { max-width: 300px; } .semantic_ui .ui.table { border: 0px solid !important; } .semantic_ui .ui.table td { padding: 0em; } Subscribe to our newsletter!

Never miss updates about new episodes.

Subscribe