So this episode addresses a big gap in the EMCrit content, namely a discussion of the myriad uses of dexmedetomine. This is one of the primary agents I use for post-intubation sedation (PAD), but also for things like NIPPV sedation and procedural sedation.
Upsides of Dexmedetomine (Precedex)
 
Downsides of Dexmedetomidine
 
Other Stuff on EMCrit

* Podcast 115 – A New Paradigm for Post-Intubation Pain, Agitation, and Delirium (PAD)
* PulmCrit Wee- Extubating the agitated patient: dexmedetomidine vs. cowboy-style?
* Dexmedetomidine to facilitate noninvasive ventilation

 
Studies

The Effect of Propofol and Dexmedetomidine Sedation on Norepinephrine Requirements in Septic Shock Patients (Critical Care Medicine: February 2019 - Volume 47 - Issue 2 - p e89–e95)
https://www.ncbi.nlm.nih.gov/pubmed/21812509
https://www.ncbi.nlm.nih.gov/pubmed/27035758

Now on to the Podcast...