The Mystery Of Mast Cell Activation Syndrome [MCAS]:
Occam's Razor, Immunity, & Treatment Failure
Dr. Lawrence Afrin 
It’s important to understand that [Occam's] Razor doesn’t say the simpler of two explanations is the more likely, nor does it say that the more popular, more widely believed, or easier to understand explanation is the more likely. It doesn’t even say that one explanation is necessarily more likely than two or more. All it says is that if one explanation can account for at least as much of the observed truth of a situation as two or more explanations, then it’s more likely that the one explanation is closer to the true explanation than the two or more explanations.[1]
~ Lawrence Afrin

The great thing about science is that it's true whether you believe in it or not.
~ Neil deGrasse Tyson
Coalescent Thinking For Chronic Treatment Failure
Jennifer's Mast Cell Activation Syndrome Story 
"Consider your life.
Now consider how your life might change if things like loud noise, heat, strong emotions or stress, odors or even being startled could cause you to have an allergic reaction. Imagine suffering allergic reactions so frequently that you prayed for just 30 seconds of real relief each day. Imagine dreading the next response, because it may bring vomiting and diarrhea, convulsions, unresponsiveness or even paralysis-like symptoms.
Jennifer Robin, who was diagnosed with mast cell activation syndrome (MCAS)[2] in 2014, faced these challenges daily until she received treatment in 2015 from the University of Minnesota Health Hematologist/Oncologist Lawrence Afrin, MD, an internationally respected expert on MCAS.
'The disease can be a life-ruiner. I was unable to work, live independently, drive, have a social life—or have much of any life,' said Jennifer."
Her Immunity Issues: 'The world just wasn’t safe for me.'
Although she was always very sensitive to allergens, Jennifer’s overall health began to nose dive in her early 20s. A Maryland resident, Jen was forced to resign from her job when a variety of physical symptoms—including severe headaches, cognitive difficulties, and fever-like problems—began to affect her health.
In 2010, Jennifer was misdiagnosed with Lyme disease. Treatment for Lyme disease did not alleviate her symptoms, which became more severe over time. Jennifer began experiencing seizure-like episodes, slurred speech, insomnia and muscle weakness.
'I was so sick and pretty much bed-bound for a couple of years. My parents had to help me to the bathroom two feet away,' Jennifer said. 'No doctor seemed to have any clue what was happening.'
In 2013, Jennifer was diagnosed with postural orthostatic tachycardia syndrome (POTS - a dysautonomia syndrome), which is marked by an increase in heart rate when standing. That same year, she was also diagnosed with Ehlers-Danlos syndrome (EDS), a group of genetic disorders that primarily affect connective tissue in skin, joints and blood vessel walls.
But neither diagnosis seemed to account for all of Jennifer’s difficulties, which continued to become more severe. At times, she felt the tissues of her throat closing—a life-threatening occurrence kno...