July 26, 2009. A Ford Windstar minivan enters the Taconic State Parkway shortly after 1:30pm and accelerates to a speed of 85 mph ... going the wrong way into oncoming traffic. Behind the wheel is 36-year-old Diane Schuler,

On February 19, 2013, a maintenance worker at the Cecil Hotel in downtown Los Angeles checks the 4 towering water tanks on the building's rooftop after complaints from guests about a strange taste and smell emanating from the supply to their rooms.

26-year-old father and oil-field worker Brandon Lawson leaves his San Angelo, TX home shortly before midnight on August 9, 2013, at the culmination of an argument with his common-law wife, Ladessa. After calling his father,

On the morning of November 1, 2007, Amanda Knox, an American college student living abroad in Perugia, Italy, returns to her apartment to find the front door open, blood in the bathroom, and her unresponsive roommate locked inside a bedroom.

On July 5, 2011, Casey Anthony was acquitted of numerous charges related to the asphyxiation death of her 3-year-old daughter Caylee in Orlando, FL, drawing outrage from the media and general public that persists to this day,

In the early morning hours of December 9, 2001, novelist and aspiring politician Mike Peterson makes a harrowing 911 call to report that his wife Kathleen has fallen down the stairs of their Durham, NC mansion and is barely breathing.

In a 2-part episode, we first delve into the unsolved Santa Rosa Hitchhiker Murders, a series of unexplained deaths throughout the 1970s involving young female victims being dumped along roadsides, a case in which there is still very little evidence.

On September 27, 1969, a young woman named Cecelia Shepard died while being rushed to the hospital after she and fellow student Bryan Hartnell were viciously stabbed as they picnicked along an isthmus on a beautiful day at Lake Berryessa in Northern Ca...

On the morning of December 26, 1996, a frantic mother named Patsy Ramsey calls 911 to report that her daughter is missing and a ransom note was left on their back staircase demanding $118,000. As authorities investigate the disappearance, however,