The story of Sheena involves a young girl orphaned after her geologist parents are killed in a cave-in while exploring the source of mystical healing soil found near the jungle in the fictional African country of Tigora.  The native Zambouli villagers immediately adopt the girl, dubbing her "Sheena," prophecied to be their savior and the future queen of the jungle.  Sheena grows up to be a strikingly beautiful woman (Tanya Roberts), learning how to communicate and control animals with her mind, ride a zebra, and other mystical arts.

Trouble brews in her territory when Prince Otwani (Trevor Thomas), an ex-football placekicker, joins in a plot to assassinate his brother, King Jabalani (Clifton Jones) so that he can gain untold riches from the fertile Zambouli lands he's been protecting.  Shaman, one of the Zambouli leaders, is framed for the killing. Still, a visiting American sports news crew, led by charismatic sports reporter Vic Casey (Ted Wass), captures the events as they happen, showing that a significant coup was in play.  Otwani, wanting the incriminating tape back at any cost, sets about capturing Vic before he can escape, but with the help of Sheena and her animal friends, Casey means to get out of the country to set the record straight.

John Guillermin directs.