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A more rapid measure of fibrinogen: a system similar to thromboelastography
December 23, 2014

For patients undergoing cardiopulmonary bypass, measures of fibrinogen can guide hemostasis therapy. Typically, fibrinogen assays take 30-60 minutes, during which therapy may be delayed. Dr. Satoru Ogawa, Department of Anesthesiology, Kyoto Prefectural Un

What do anesthesia residents think about the quality of supervision?
December 22, 2014

Those of us in anesthesiology teaching programs supervise resident physicians. How well do we do? Dr. Franklin Dexter, Division of Management Consulting, Department of Anesthesia, University of Iowa, Iowa City, Iowa, and colleagues from the Department of

January 2015: Anesthesia & Analgesia
December 18, 2014

The January issue of Anesthesia & Analgesia has just posted. Dr. Steven Shafer, editor-in-chief, Anesthesia & Analgesia: In 2008 Filho proposed an instrument for measuring faculty supervision. In this issue of Anesthesia & Analgesia De Oliveira Jr. and

Nerve blocks may be helpful in children undergoing VP shunt revision
December 17, 2014

There are many challenges for children requiring surgery, but to the extent possible pain should not be among them. In the current edition of A&A Case Reports, Drs. Michael R. King and T. Anthony Anderson, Department of Anesthesia, Critical Care and Pain

Variation in the pulse oximetry plethysmographic waveform: a surrogate for left atrial fluid responsiveness
December 16, 2014

Intrathoracic pressure changes during ventilation. Widely appreciated, but less well understood, is how changes in intrathoracic pressure change preload and cardiac output. If you ask a resident what will happen when the ventilator gives a positive pressu

Multiple vs. single injection of the proximal sciatic nerve
December 15, 2014

Regional anesthesia should come on more quickly when the local anesthetic spreads circumferentially around the nerve. There is evidence for this with popliteal blocks, but not for blocks of the proximal sciatic nerve. The proximal sciatic nerve is the lar

Regional oximetry: the wave of the future?
December 11, 2014

Although traditional pulse oximetry is a standard monitor in anesthesia, it is limited in its ability to detect tissue hypoxia. Typical interventions used to increase SpO2 may not necessarily improve tissue oxygenation, particularly in ischemic organs. Re

Glucose, isoflurane, and caspase-3 activation
December 10, 2014

Is the elderly brain susceptible to potential neurotoxic effects of inhalational anesthetics? Clinical studies are inconclusive, but isoflurane can induce the accumulation of reactive oxygen species (ROS), mitochondrial dysfunction, and decrease in ATP va

An analysis of second-line uterotonic use in the United States
December 09, 2014

Oxytocin is routinely administered during the third stage of labor for prophylaxis against postpartum hemorrhage, a leading cause of morbidity and mortality. If the uterus does not adequately contract in response to oxytocin administration, other drugs ca

Thoughts about resuscitation during the time of the ancient Greeks
December 08, 2014

Though we might think of resuscitation as being a purely modern phenomenon, there’s evidence that some of the concepts of resuscitation have been known for more than 1,000 years. Were some of the concepts of resuscitation known as early as during the ti