Informed Dissent

Informed Dissent


Latest Episodes

Talking baseball with former Major Leaguer Greg Pryor
December 29, 2025

Informed Dissent with Dr. Jeff Barke and Dr. Mark McDonald We set aside health care and politics for a festive Christmas and New Year conversation with former Major Leaguer and author Greg Pryor. He recounts an unlikely rise from undrafted teen to 10 ML

Despite 2020’s medical crises, vaccine mandates persist in California
December 22, 2025

Informed Dissent with Dr. Jeff Barke and Dr. Mark McDonald Vaccine mandates continue across California despite the medical crises of recent years. Alix Mayer of the Free Now Foundation leads efforts to challenge mandates, expand exemptions, and defend m

When the holidays hurt: Coping with Christmas sadness
December 15, 2025

Informed Dissent with Dr. Jeff Barke and Dr. Mark McDonald Christmas is often portrayed as joyful, but for many it brings grief, loneliness, and emotional strain. This piece explores why the holidays can hurt and offers practical, compassionate ways to

How modern medicine lost public trust—and how to heal it
December 08, 2025

Informed Dissent with Dr. Jeff Barke and Dr. Mark McDonald Medicine faces a crisis of trust, effectiveness, and purpose as chronic illness rises and life expectancy falls. Jeff and Mark speak with Dr. Aaron Kheriaty about what went wrong in modern healt

The testosterone gap shaping modern dating and masculinity
December 01, 2025

Informed Dissent with Dr. Jeff Barke and Dr. Mark McDonald A growing health crisis is reshaping masculinity and dating as young men experience historically low testosterone. Physicians explore cultural, lifestyle, and environmental drivers, from screens

Inflammation, its causes, and how to prevent it
November 24, 2025

Informed Dissent with Dr. Jeff Barke and Dr. Mark McDonald Jeff explores inflammation with Dr. Barry Sears, revealing how chronic low-level immune activation silently damages bodies and minds. He highlights the AA to EPA ratio, the power of omega-3s, an

Pamela Garfield: The truthful therapist
November 17, 2025

Informed Dissent with Dr. Jeff Barke and Dr. Mark McDonald A therapist challenges current trends in youth gender medicine, stressing honesty, holistic care, and family involvement. Physicians warn about rapid medicalization and urge careful evaluation.

Eric Moutsos: Truth seeker or conspiracy theorist?
November 10, 2025

Informed Dissent with Dr. Jeff Barke and Dr. Mark McDonald Former police officer Eric Moutsos challenges official narratives and defends the right to question authority. Physicians echo his call for transparency, free speech, and honest inquiry. They ar

Resuscitating nursing: The courage to dissent
November 03, 2025

Informed Dissent with Dr. Jeff Barke and Dr. Mark McDonald Ashley Grogg, co-host of Nurses Out Loud, shares how informed dissent can revive nursings true mission. In Resuscitating Nursing: A Tactical Roadmap for Nurses Who Refuse to Be Silenced, she ur

Bitcoin for dummies
October 27, 2025

Informed Dissent with Dr. Jeff Barke and Dr. Mark McDonald Bitcoin is often confusing, yet understanding it matters. Brian Harrington, a Bitcoin and real estate investor since 2015, shares why owning Bitcoin offers financial protection. As trust in gove