Nurses Out Loud with Kimberly Overton, BSN, RN – Pilot incapacitation is defined as the inability of a pilot to carry out their normal duties during the flight due to the effects of physiological factors. This may occur as a result of hypoxia, insufficient oxygenation while at increased altitudes, inhalation of smoke or fumes, GI problems such as severe gastroenteritis, or a medical emergency such as a heart attack...