In episode 541, James and Mike get into a powerful discussion of placebo. We talk about the evidence around placebo, the placebo effect, the placebo group effect/response and we try to put it all into

In episode 540, James and Mike invite Jennifer Young to go over all the evidence we have for what antibiotics to choose for bladder infections. The evidence clearly shows that the antibiotics we have

In episode 538, James and Mike discuss the great (but pretty much silly) egg controversy. We go over the best available evidence for eggs which is at best not great. We talk about the cohorts, the eff

In episode 537, Mike and James invite Ricky Turgeon back to the podcast to talk about the impact of the influenza vaccination on cardiovascular events in both primary and secondary prevention. The bes

In episode 536, Mike and James talk about 4 questions Is any bacteriuria associated with altered mental state? Does treating ASB improve/prevent clinical outcomes? Does treating ASB improve alte

In episode 535, Mike and James work through all the evidence and come up with the definitive (in our minds) answer as to whether or not statins cause muscle symptoms. They likely do in 1% of people, b

In episode 534, Mike and James bring Jamie Falk to go through all the evidence for continuous glucose monitors that use subcutaneous sensors. There certainly seems to be evidence of benefit for T1DM b

In episode 532, Mike and James bring Mike Kolber in to chat about potential treatments for anal fissures. We discuss the evidence for topical nitroglycerin, topical calcium channel blockers and topica

In episode 531, Mike and James chat with Samantha Moe yet again. In this podcast we go over all the best evidence for whether or not inhalers help with post-infectious cough in adults without asthma.

In episode 530, Mike and James welcome Samantha Moe back to the podcast to do an end of the year podcast. In this podcast we discuss the evidence around New Years resolutions. We discuss what are the