Don’t ask for things to happen as you would like them to, but wish them to happen as they actually do, and you will be all right. (Ench 8)
This passage, and several other similar passages within the Stoic texts, present a huge, sometimes insurmountable, stumbling block for many people when they begin to study and practice Stoicism. As Simplicius notes in his commentary on this passage:

But perhaps this injunction to ‘wish for it to happen as it happens’ will seem to some people to be harsh and impossible. What right thinking human being wishes for the occurrence of the widespread bad effects resulting from the universe – for instance, earthquakes, deluges, conflagrations, plagues, famine and the destruction of all sorts of animals and crops? Or the impious deeds performed by some human beings on others – the sacking of cities, taking prisoners of war, unjust killings, piracy, kidnapping, licentiousness, and tyranni cal force, culminating in compelled acts of impiety? …These things and others of this sort – of which there has been an excess in our own lifetime – who would want to hear of them, let alone see them, take part in them or ‘wish them to happen as they happen’, except a malevolent person and a hater of all that is fine?[1]

 
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[1] Brennan, T., & Brittain, C. (2002). Simplicius: On Epictetus’ Handbook 1-26. Cornell University Press. p. 79