In this episode, we have some special guests, Dr. Daniel Dodson, and one of our medical students, Aneri Patel, talk to us about Kawasaki disease. Special thanks to Dr. Natasha Nakra for content review.

Key points:

-Vasculitis with the clinical features in the mnemonic CRASH and Burn

-Incomplete Kawasaki has lab features including elevated ESR and CRP, thrombocytosis, hypoalbuminemia, anemia, elevated ALT, leukocytosis, and sterile pyuria.

-Treatment is to prevent coronary artery aneurysms with IVIG and aspirin.

References:

AAP Pediatrics in Review

https://publications.aap.org/pediatricsinreview/article/39/2/78/35139/Kawasaki-Disease?autologincheck=redirected

Infliximab and Kawasaki

https://www.sciencedirect.com/science/article/pii/S2352464221002704?via%3Dihub

Principles and Practices of Infectious Diseases, 6th edition