Classes of insulin and different treatment regimens are discussed in the third episode of a 3-part series on diabetes. This episode also marks the conclusion of our coverage of the “Big Three” of modern medicine (hypertension, dyslipidemia, and diabetes), and with it, we make an official announcement of the launch of the Family Pharm Podcast to the world (aka Facebook)!

 

Class
Drug
Onset
Peak
Duration

Very Rapid-acting Insulin Analogues
insulin aspart

(NovoRapid)
10–15 min
60–90 min
4–5 h

insulin glulisine

(Apidra)

insulin lispro

(Humalog)

Rapid-acting Insulin
insulin regular

(Humulin R, Novolin ge Toronto)
30–60 min
2–4 h
5–8 h

Intermediate-acting Insulin
insulin NPH

(Humulin N, Novolin ge NPH)
1–2 h
5–8 h
14–18 h

Long-acting Insulin Analogues
insulin detemir

(Levemir)
1.5 h
Flat, no discernible peak
24 h

insulin glargine

(Lantus)

Mixed (regular/NPH) Human Insulin
insulin regular/insulin NPH

Humulin 30/70,

Novolin ge 30/70, 40/60, 50/50
Combination of individual components

Mixed Insulin Analogues
insulin lispro/lispro protamine

Humalog Mix25, Humalog Mix50
10–15 min
Not available
Not available

Mixed Insulin Analogues
insulin aspart/aspart protamine

NovoMix 30
10–15 min
60–90 min
15–18 h

Classes of insulin preparations. Adapted from Therapeutic Choices 6th edition.

CDA guideline on insulin for Type 1 diabetes, including description of basal-bolus regimen by carb counting:

• 
  
• http://guidelines.diabetes.ca/Browse/Chapter12
  

Examples of insulin regimens from CDA:

• 
  
• http://guidelines.diabetes.ca/Browse/Appendices/Appendix3
  

Self monitoring:

• 
  
• http://guidelines.diabetes.ca/executivesummary/ch9
  

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