In the US, among women at high risk for acquiring HIV infection, only around 2% have initiated PrEP. What are the patient, provider, and system barriers to increased PrEP uptake in this vulnerable population? What can clinicians do to overcome these barriers?

In this issue, Dr. Rachel Scott, Scientific Director of Women's Health Research at the MedStar Health Research Institute and Assistant Professor of Obstetrics and Gynecology at the Georgetown University School of Medicine, provides some answers.