Dr. Paul Alexander Liberty Hour – DISEASE 'X' WARNING: Metabolic syndrome is disease X & is the gravest health challenge facing Western nations, e.g., the US, Canada, UK, as well as Caribbean nations. A cluster of conditions that occur together, increasing the risk of heart disease, stroke, and type 2 diabetes, includes increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels.