As part of the Interventions Testing Program run by the National Institutes of Health, five agents—resveratrol, green tea extract, medium chain triglycerides, curcumin, and oxaloacetic acid—were tested at three independent testing sites in over 1000 mice per agent tested. The testing found no benefit to any of the agents. I interpret these findings to mean that we can reasonably conclude that there will be no benefit in humans. I explain why and when we can use animal studies to inform human recommendations, as I believe we can here.

Study PMID: 22451473

For more about the resveratrol story, check out Brad Stanfield’s summary here: https://www.youtube.com/watch?v=JAFnD27ffqE

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